NATIONAL
INSTITUTES OF HEALTH, DEPARTMENT OF HEALTH AND HUMAN SERVICES
AUTHORIZATION:
Public
Health Service Act, Section 305(a), 410, 411, and 414, Public Law
78-410, 42 U.S.C. 241, as amended; Public Law 100-607, 42 U.S.C.
285, 285a and 285a-3; Public Law 99-500.
To
provide an organizational focus and stimulus for the highest quality
cancer research that effectively promotes interdisciplinary cancer
research aimed toward the ultimate goal of reducing cancer incidence,
mortality and morbidity. The Cancer Center Support Grant (CCSG)
provides the resources and infrastructure to facilitate the coordination
of interdisciplinary programs across a broad spectrum of research
from basic laboratory research to clinical investigation to population
science. The CCSG supports salaries for scientific leadership of
the Center, shared resources for funded center investigators, certain
administrative costs, planning and evaluation, and developmental
funds for new recruitments and feasibility studies.
TYPES
OF ASSISTANCE:
Project Grants. Place Cursor Here for Definition
USES
AND USE RESTRICTIONS:
In general, CCSGs do not
support research projects directly but are used to enhance the ongoing
cancer research and to strengthen the existing research base according
to the "Policies and Guidelines Relating to the Cancer Center Support
Grant."
ELIGIBILITY REQUIREMENTS:
Applicant Eligibility:
Any nonprofit institution within the United States with a peer-reviewed
cancer research base of 3.0 million dollars in direct costs may
apply for a Cancer Center Support Grant.
Beneficiary Eligibility:
University, college, public agency or research institution in
the U.S.
Credentials/Documentation:
The application requests documentation concerning the qualifications
of the principal investigators and associates, pertinent budget
information and justification for the support of this proposed
grant. Methods to be utilized are outlined in the application
materials. Costs will be determined in accordance with HHS Regulations
45 CFR, Part 74, Subpart Q, and for State and local governments
in accordance with OMB Circular No. A-87.
Pre-application
Coordination: Not applicable. This program is
excluded from coverage under E.O. 12372.
Application Procedure:
Method of Application: Form PHS-398 (Rev. May 2001) can be obtained
from the, Division of Extramural Outreach and Information Resources,
National Institutes of Health, 6701 Rockledge Drive, Bethesda,
MD 20892-7910. Telephone (301)435-0714; e-mail ASKNIH@odrockml.od.nih.gov.
In addition, supplemental instructions for applications are contained
in the Cancer Center Support Grant Guidelines which can be obtained
by writing to the Cancer Centers Branch, 6116 Executive Boulevard,
Suite 700, MSC 8345, Bethesda, MD 20892-8345 or by calling (301)496-8531.
Generally, the potential applicant should send a letter of intent
to the National Cancer Institute, submitting a CCSG application
to the same address for review (see Guidelines for CCSGs). Completed
applications should be submitted to the Center for Scientific
Review, National Institutes of Health, 6701 Rockledge Drive, Bethesda,
Maryland 20892. This program is subject to the provisions of 45
CFR, Part 92 for State and local governments and OMB Circular
No. A-110 for nonprofit organizations.
Award Procedure:
Grants are funded based on scientific merit, program relevance,
and program balance and are made annually. Initial award provides
funds for the first budget period (usually 12 months) and Notice
of Grant Award (Form PHS 1533) indicates support recommended for
the remainder of the project period, allocation of Federal funds
by budget categories and special conditions, if any.
Deadlines:
Cancer Center Support Grant Applications (P30 mechanism): Renewals,
New and Supplemental: February 1, June 1, and October 1. Cancer
Center Planning Grant Applications (P20 mechanism): January 14.
Range of Approval/Disapproval
Time: Core Grants: Approximately 10 months.
Appeals:
A principal investigator may question the substantive or procedural
aspects of the review of his/her application by communicating
with the staff of the Institute. A description of the NIH Peer
Review Appeal procedures is available on the NIH home page www.nih.gov/grants/guide/1997/97.11.21/n2.html.
Renewals:
Same procedure as new applications.
ASSISTANCE CONSIDERATIONS:
Formula and Matching
Requirements: This program has no statutory
formula or matching requirements.
Length and Time Phasing
of Assistance: Up to 5 years of support may
be requested. Grants may be awarded up to 5 years based on competitive
peer review.
POST ASSISTANCE REQUIREMENTS:
Reports:
Progress reports are required each year. An annual financial status
report is requested 90 days after the end of the budget period.
Special reports may be requested by DHHS. Terminal reports are required
90 days after the end of a project.
Audits:
"In accordance with the provisions of OMB Circular No. A- 133
(Revised, June 24, 1997), Audits of States, Local Governments,
and Nonprofit Organizations, nonfederal entities that expend financial
assistance of $300,000 or more in Federal awards will have a single
or a program-specific audit conducted for that year. Nonfederal
entities that expend less than $300,000 a year in Federal awards
are exempt from Federal audit requirements for that year, except
as noted in Circular No. A-133." In addition, grants and cooperative
agreements are subject to inspection and audits by DHHS and other
Federal government officials.
Records:
Expenditures and other financial records must be retained for
3 years from the day on which the grantee submits the last financial
status report for the report period.
FINANCIAL INFORMATION:
Account Identification:
75-0849-0-1-552.
Obligations:
(Grants) FY 01 est $279,731,000; FY 02 est $304,799,000; and FY
03 est $355,808,000.
Range
and Average of Financial Assistance:
$11,600 to $7,533,084; Average: $3,008,000.
Fiscal year 2001 Centers
funded 93 total Centers - 60 CORE, 31 SPORE, and 2 Specialized Centers.
Fiscal year 2002 Centers est 102 total Centers 61 CORE, 37 SPORE,
and 4 Specialized Centers. Fiscal year 2003 Centers est. 110 total
Centers 61 CORE, 45 SPORE, and 4 Specialized Centers. Cancer Centers
are supported through the P30 grant mechanism as Cancer Center Support
Grants (CCSGs), which fall into three categories as follows: cancer
centers, clinical cancer centers and comprehensive cancer centers.
In addition, applications for P20 Cancer Center Planning Grants
are accepted once a year for competitive review. Policies and guidelines
governing the main instrument of support, the Cancer Center Support
Grant, have recently been revised; separate guidelines for the P20
Cancer Center Planning Grants are also available. In fiscal year
2001, 61 cancer centers are estimated to receive these grants, and
in 2002, 62 centers are anticipated to be funded. In addition to
the P30 Cancer Center Support Grants, the program supports the planning
efforts of five academic and research institutions with P20 planning
grants. Six are anticipated to be supported with these planning
grants in fiscal year 2001 and seven in fiscal year 2002. Fiscal
year 2003 is expected to be a very active year for planning grants;
six applications have been submitted for review. The cancer centers
program currently supports 60 cancer centers. These all represent
the most research intensive institutions in the country. However,
considerable progress is being made in working with smaller, less
research intensive institutions in areas of the country that have
not NCI designated cancer centers. There are at least 15 institutions
that have the potential to be excellent small cancer centers located
in states without centers at this time. The NCI will work with these
institutions very closely in t he future.
Headquarters Office:
Program Contact: Dr. Linda Weiss, Chief, Cancer Centers Branch,
Office of Centers, Training and Resources, National Institutes
of Health, Department of Health and Human Services, 6116 Executive
Boulevard, Suite 700, Bethesda, MD 20892. Telephone: (301) 496-8531.
Grants Management Contact: Leo F. Buscher, Jr., Grant Management
Officer, National Cancer Institute, National Institutes of Health,
Department of Health and Human Services, EPS 234, Bethesda, MD
20892. Telephone: (301) 496-7753. Use the same numbers for FTS.
Web Site Address: http://www.nci.nih.gov/cancercenters
EXAMPLES OF FUNDED PROJECTS:
CCSG awards to Memorial
Sloan-Kettering Institute (comprehensive cancer center); to University
of Alabama (comprehensive cancer center), to the St. Jude Children's
Research Hospital (clinical cancer center), to the University of
Utah (clinical cancer center), to the Salk Institute (cancer center),
and to the Wistar Institute, cancer center.
CRITERIA FOR SELECTING PROPOSALS:
The major elements in
evaluating applications include the following: (1) An adequate base
of established programs of high quality in laboratory and clinical
cancer research; (2) research activity in a variety of disciplines,
and evidence of high degree of interdisciplinary coordination, interaction
and cooperation among center members; (3) appropriate and adequate
organization and facilities for the conduct and evaluation of center
activities; (4) a qualified director with adequate authority; and
(5) an adequate commitment of the parent institution or institutions
to the cancer center. The center should be recognized as a major
element within the organizational structure.
