AGENCY
FOR TOXIC SUBSTANCES AND DISEASE REGISTRY, DEPARTMENT OF HEALTH
AND HUMAN SERVICES
AUTHORIZATION:
Comprehensive
Environmental Response, Compensation, and Liability Act (CERCLA)
of 1980, as amended; Superfund Amendments and Reauthorization Act
of 1986, Sections 104 (i)(5)(A) and (15), Public Law 99-499; 42
U.S.C. 9604 (i)(5)(A) and (15); Great Lakes Critical Programs Act
of 1990, Section 106, Subsection 118(e); 33 U.S.C. 1268(e)(3).
To:
(1) Build upon and amplify the results from past and on-going research
in the Great Lakes basin; (2) develop information, databases and
research methodology that will provide long-term benefit to human
health effects research in the Great Lakes basin; (3) develop direction
for future health effects research; (4) provide state local health
officials: the concerned public and their medical health care professionals;
(5) in concert with State and local health offices increase the
public awareness regarding the potential health implications of
the toxic pollution problem in the Great Lakes basin; and (6) coordinate
as necessary with relevant Public Health Service (PHS) research
programs and activities, including those of the Food and Drug Administration
(FDA), Centers for Disease Control and Prevention (CDC), National
Institutes of Health (NIH), and the Indian Health Service (IHS),
as well as the Environmental Environment Protection Agency (EPA)
and State and local health departments, to ameliorate adverse public
health impacts of persistent toxic substances in the Great Lakes
basin.
TYPES
OF ASSISTANCE:
Project Grants. Place Cursor Here for Definition
USES
AND USE RESTRICTIONS:
To conduct research on
the impact on human health of fish consumption in the Great Lakes
region. This Program of Research will focus on populations which
have been identified to have a higher risk of long-term adverse
health effects from exposure to contaminants in Great Lakes fish,
i.e., Native Americans, sport anglers, urban poor, the elderly,
Asian Americans, racial/ethnic minority populations, fetuses, and
nursing infants of mothers who consume contaminated Great Lakes
fish. Priority areas of research for this program include: 1. Characterizing
exposure and determining the profiles and levels of Great Lakes
contaminants in biological tissues and fluids in high-risk populations;
2. Identifying sensitive and specific human health endpoints, i.e.,
reproductive/developmental, behavioral, endocrinologic, and immunologic
effects and correlating them to exposure to Great Lakes contaminants;
and 3. Determining the short- and long-term risk(s) of adverse health
effects in children which result from parental exposure to Great
Lakes contaminants. Proposed projects covering these priority areas
should include strategies (risk communication) to inform susceptible
populations about the potential human health impact of consuming
contaminated fish from the Great Lakes. Based upon research findings,
longer term priority areas may include, but are not limited to:
1. Investigating the feasibility of, or establishing, registries
and/or surveillance cohorts in the Great Lakes region; and 2. Establishing
a chemical mixtures database with emphasis on tissue and blood levels
to identify new cohorts, conduct surveillance and health effects
studies, and establish registries and/or surveillance cohorts.
ELIGIBILITY REQUIREMENTS:
Applicant Eligibility:
Eligible applicants are the official public health agencies or their
bona fide agents or instrumentalities and political subdivisions
thereof, which may include State universities, State colleges, State
research institutions, State and local health departments, and federally-recognized
Indian tribal governments located in the Great Lakes States. This
includes Illinois, Indiana, Michigan, Minnesota, Ohio, Pennsylvania,
New York and Wisconsin and is consistent with Section 106, Subsection
118(e) of the Great Lakes Critical Programs Act of 1990 (33 U.S.C.
1268(e)(3)).
Beneficiary Eligibility:
Native Americans, Minority Groups, Sport Anglers, Urban Poor,
Individuals and Families who consume contaminated Great Lakes
Fish.
Credentials/Documentation:
Costs will be determined in accordance with OMB Circular No. A-87
for State and local governments.
Pre-application
Coordination: None. An environmental impact
statement is not required for this program. This program is excluded
from coverage under E. O. 12372.
Application Procedure:
Applicants must use application Form 5161-1. Application packets
are available from: Acquisition and Assistance Branch A, Procurement
and Grants Office, Centers for Disease Control and Prevention,
2920 Brandywine Road, Room 3000, Atlanta, GA 30341. By formal
agreement, the CDC Grants Management Branch will act on behalf
of ATSDR on this matter.
Award Procedure:
The Assistant Administrator, ATSDR, has final authority to approve
funding of applications. When an application is approved for funding,
the Grants Management Officer, CDC, acting as agent for ATSDR,
will prepare a Notice of Grant Award.
Deadlines:
Contact the Headquarters Office identified below for application
deadlines.
Range of Approval/Disapproval
Time: Approximately 60 to 90 days.
Appeals:
None.
Renewals:
Awards are made for project periods of 1 to 3 years with 12-month
budget periods. Renewals awards cannot be made beyond the project
period without competition.
ASSISTANCE CONSIDERATIONS:
Formula and Matching
Requirements: This program has no statutory
formula or matching requirements.
Length and Time Phasing
of Assistance: The awards will be made for
12-month budget periods within a project period of 1 to 3 years.
Continuation awards within the project period are made on the
basis of satisfactory progress and availability of funds.
POST ASSISTANCE REQUIREMENTS:
Reports:
Annual progress and financial status reports are required no later
than 90 days after the end of each budget period. Final financial
status and performance reports are required 90 days after the end
of the project period.
Audits:
In accordance with the provisions of OMB Circular No. A- 133 (Revised,
June 24, 1997), "Audits of States, Local Governments, and Nonprofit
Organizations," nonfederal entities that expend financial assistance
of $300,000 or more in Federal awards will have a single or a
program-specific audit conducted for that year. Nonfederal entities
that expend less than $300,000 a year in Federal awards are exempt
from Federal audit requirements for that year, except as noted
in Circular No. A-133. In addition, grants and cooperative agreements
are subject to inspection and audits by HHS and other Federal
officials.
Records:
Detailed and accurate records of travel expenditures, personnel
hours and all other costs will be retained for 10 years in accordance
with EPA's "Superfund Financial Management and Recordkeeping Guidance
for Federal Agencies." Such documents may be required to provide
the basis of cost recovery actions or other litigation. Additionally,
this documentation must be available for audit or verification
upon the request of the Inspector General.
FINANCIAL INFORMATION:
Account Identification:
75-8252-0-1-551.
Obligations:
(Grants) FY 01 $1,125,000; FY 02 est $1,187,000; and FY 03 est
$3,000,000.
Range
and Average of Financial Assistance:
From $72,000 to $175,000; Average: $119,000.
In fiscal year 2001, funding
was provided for 10 competing awards. It is anticipated that there
will be 10 noncompeting continuation awards in fiscal years 2002
and 2003.
REGULATIONS, GUIDELINES, AND
LITERATURE:
Regulations governing
this program are set forth in 45 CFR 92 and 40 CFR 35, subpart O.
Guidelines are available in the application kit. PHS Grants Policy
Statement No. 94-50,000 (Revised) April 1, 1994.
INFORMATION CONTACTS:
Regional or Local
Office: Not applicable.
Headquarters Office:
Program Contact: Dr. Heraline E. Hicks, Division of Toxicology,
Agency for Toxic Substances and Disease Registry, 1600 Clifton
Road, NE, Mail Stop E-29, Atlanta, Georgia 30333. Telephone: (404)
489-0717. Fax: 404-498-0094. E-mail address: HEH2@cdc.gov. Grants
Management Contact: Ms. Edna Green, Acquisition and Assistance
Branch A, Procurement and Grants Office, Centers for Disease Control
and Prevention, 2920 Brandywine Road, Room 3000, Atlanta, GA 30341.
Telephone: (770) 488-2743. Fax: (770) 488-2777; Email: ecg4@cdc.gov.
Web Site Address: http://www.atsdr.cdc.gov
EXAMPLES OF FUNDED PROJECTS:
(1) The New York State
Angler Cohort Study: Exposure Characterization and Reproductive
and Developmental Effects; (2) Great Lakes Fish as a Source of Maternal
and Fetal Exposure to Chlorinated Hydrocarbons; (3) An Assessment
of a Human Population at Risk: The Impact of Consuming Contaminated
Great Lakes Fish on Native American Communities; (4) Cognitive and
Motor Effects of PCB Exposure in Older People from the Michigan
Fish Eaters Cohort: Emphasis on the Role of Ortho-Substituted Congeners;
(5) Contribution of Nursing to Behavioral Changes in Offspring of
Mothers Who Consumed Lake Ontario Fish: Two Methodological Approaches;
(6) Health Risks from Consumption of Great Lakes Fish; and (7) Assessing
Effects of Human Reproductive Health of PCB Exposure via Consumption
of Great Lakes Fish. Three grants were awarded to State Health Departments
for the following projects: (1) PCB and DDE Exposure among Native
American Men from Contaminated Great Lakes Fish and Wildlife; (2)
Consortium for the Health Assessment of Great Lakes Sport Fish Consumption;
and (3) Michigan Great Lakes Health Studies.
CRITERIA FOR SELECTING PROPOSALS:
Applications will be reviewed
and evaluated according to the following criteria: Proposed Program;
Program Personnel; Applicant Capability; and Program Budget (Not
Scored).
